Which cell line is commonly used in biotechnology studies?

Chinese hamster ovary (CHO) cells are widely used in biotechnology studies, particularly for the production of recombinant proteins and monoclonal antibodies. This is primarily due to their ability to perform post-translational modifications that are similar to those in human cells, which is critical for the functionality of many therapeutic proteins.

CHO cells are also advantageous because they grow rapidly and can be maintained in culture for long periods, making them ideal for industrial and research applications. Their genetic tractability allows scientists to manipulate their DNA to produce specific proteins or study cellular functions, thus significantly aiding various research and biotechnology endeavors.

Furthermore, CHO cells have a well-established safety profile and regulatory history, making them a preferred choice for pharmaceutical production. This combination of attributes makes CHO cells a cornerstone in the field of biotechnology.